MioPets®
MioPets® is a product with pronounced antimicrobial and anti-inflammatory properties that helps strengthen the immune system of pets.
Pharmacological Action
Active ingredient: Recombinant protein LEAP-2 (2 mg/ml)
Clinical Effect
Antimicrobial: The peptide binds cationically to the membranes of bacteria and fungi, forming pores and causing their death. It reduces bacterial load, is used for the prevention of wound and skin infections, and decreases the recurrence of cystitis and otitis.
Immunomodulatory: Enhances phagocytosis by neutrophils/macrophages. Increases the activity of CD4⁺/CD8⁺ T cells. Rapidly "boosts" innate and adaptive immunity without causing immunosuppression.
Anti-inflammatory: Corrects cytokine balance: ↓ IL 1β, IL 6, TNF α; ↑ IL 10. Controls excessive inflammation → less swelling and pain, promoting complication-free tissue healing.
Reparative: Optimal inflammation level + low microbial load → accelerates granulation tissue growth and remodels collagen. Shortens healing times for postoperative and traumatic wounds by 20–30%.
Normalizes appetite. LEAP-2 competes with ghrelin for the GHSR 1a receptor, balancing hunger and satiety signals. Restores a healthy appetite in weakened animals and reduces stress-induced overeating.
Supports the reproductive system, strengthens the antimicrobial barrier in the reproductive tract, reduces colonization of the uterus, ovaries, and appendages. A moderate cytokine profile protects gonadal tissues from chronic inflammation, decreases the risk of endometritis, pyometra, and epididymitis, and increases the success rate of pregnancies and offspring viability.
Benefits of MioPets®
MioPets® is manufactured according to GMP quality standards: each vial undergoes microbiological testing, and the active protein LEAP-2 has a purification level of over 98%. Thanks to this, the product is suitable for cats, dogs, and small domestic animals of almost any age — from young animals (8 weeks and older) to elderly pets. High tolerability. In multicenter observations, adverse reactions were recorded in less than 1% of cases and were limited to short-term tenderness at the injection site; no systemic complications were observed. Comprehensive effect. The use of the product simultaneously inhibits the growth of pathogenic microbes, balances "emergency" inflammation, and activates key immune cells. Due to this triple protection, animals require fewer long-term courses of antibiotics and recover faster after surgeries and illnesses.
Strengthening Immunity
After administration of MioPets®, the protein rapidly enters the bloodstream and binds to innate immune cells. Within 24 hours, blood tests show increased phagocytic activity of neutrophils and a moderate rise in CD4⁺ T lymphocytes. This means your pet’s body receives ‘reinforcements’ against bacterial and viral attacks almost instantly — without the delays typical of oral supplements.
Why is the effect faster than oral supplements?
• Bypasses the gastrointestinal tract. The injection delivers the protein directly into the bloodstream, avoiding degradation in the stomach and losses during absorption.
• High bioavailability (≈ 95%). LEAP-2 does not require hepatic ‘repackaging’ and quickly reaches immune organs.
• Native structure. The molecule mimics a natural peptide, making it instantly recognizable to immune cell receptors.
Conclusion:
MioPets® activates both innate and adaptive immunity within the first 24 hours, forming an effective barrier against infections and accelerating recovery.
Postoperative Period
A surgical incision always opens the 'gates' for pathogens. MioPets® destroys the membranes of the most common wound infection agents (Staphylococcus spp., Pseudomonas spp.) while simultaneously reducing excessive TNF-α production. Clinical observations show that animals receiving the product immediately after surgery have 2–3 times fewer purulent-inflammatory complications, and the stitches appear cleaner as early as the second day.
Synergy with antibiotic therapy
• MioPets® disrupts bacterial membranes, improving the penetration of β-lactams and fluoroquinolones → the dose of traditional antibiotics can be reduced by 25–30% without loss of effectiveness.
• Lower antibiotic load — lower risk of dysbiosis and microbial resistance.
Result
Through a combination of direct antimicrobial action and gentle inflammation control, MioPets® forms a reliable “sanitary cordon” around the surgical wound, reducing the frequency of complications by 2–3 times and accelerating the pet’s full recovery.
Reproductive System
Supporting the reproductive system. Infections of the uterus and testicles are among the key causes of infertility and weak offspring. LEAP-2 reduces bacterial colonization of the vagina and reproductive appendages, protecting against inflammation of the endometrium and epididymis. In breeding kennels, a course of MioPets® administered before mating increased pregnancy success rates by 12–15%, and newborns demonstrated better weight gain during the first weeks of life.
Why is immune protection critical for reproductive organs?
• Open microbial access: the vagina and prepuce are constantly exposed to environmental bacteria such as E. coli, Staphylococcus spp., and Proteus spp.
• Delicate mucosa: the endometrium and epididymis are rich in blood vessels; even minor inflammation (endometritis, orchiepididymitis) disrupts spermatogenesis and embryo implantation.
• Chronic subclinical infections: they often show no obvious symptoms but reduce fertility quietly — fewer mature oocytes, reduced sperm motility, early resorptions.
Conclusion
MioPets® creates a local antimicrobial barrier and regulates tissue inflammation in the reproductive organs, improving fertility by 12–15%, reducing early embryonic losses, and yielding healthier offspring.
Normalization of Metabolism and Protein-Energy Balance
A healthy metabolism is the foundation of strong immunity, muscle strength, and quality coat. Chronic inflammation, hidden infections, and stress factors often ‘steal’ nutrients, shifting the pet’s body into a catabolic state (breaking down its own proteins). MioPets® helps break this vicious cycle and restore a healthy metabolic function.
How does MioPets® work?
Reducing hidden inflammation background:
— When pro-inflammatory cytokines (TNF-α, IL-6) decrease, less energy is wasted fighting microbes, and more calories are directed toward recovery.
— Amino acids and glucose are redirected to rebuild muscles and produce antibodies.
Improving nutrient absorption:
— LEAP-2 reduces bacterial load in the gut and normalizes the microbiota.
— Less intestinal inflammation → more nutrients absorbed into the bloodstream.
Regulating hunger and satiety hormones:
— Competing with ghrelin at the GHSR-1a receptor, LEAP-2 balances appetite swings: reduces overeating during stress and stimulates appetite in weakened animals.
— Stable feeding promotes maintaining a healthy diet and weight.
Supporting protein synthesis:
— With fewer catabolic cytokines, the body shifts from muscle breakdown to muscle building.
— With sufficient amino acids, the animal gains muscle mass faster and improves endurance.
Conclusion:
MioPets® not only boosts immunity but also redirects metabolic pathways to support tissue repair instead of constant fighting hidden inflammation, making it a valuable tool for maintaining a healthy protein-energy balance.
Safety
High purity:
The product is manufactured according to GMP standards; free of antibiotics and hormones.
Low incidence of side effects recorded in a multicenter study (268 animals). No systemic complications detected.
No antibiotic resistance:
MioPets® destroys microbial membranes without affecting classical antibiotic resistance mechanisms.
Compatibility: Well tolerated when combined with vaccines, NSAIDs, and most antibiotics (based on veterinarian's decision).
The product belongs to safety category 4 (the safest level).
Contraindications and Precautions
When administered according to prescribed doses and recommendations, MioPets® is generally well tolerated by animals. However, there are situations requiring special attention:
Allergic reactions to proteins.
Animals previously identified with hypersensitivity to protein preparations should undergo testing for possible allergic reactions under specialist supervision.
Severe liver or kidney disease.
Since the active substance may be metabolized and excreted differently in cases of organ failure, additional monitoring (blood tests, ultrasound, etc.) is necessary.
Immunosuppressive therapy.
If the pet is receiving immunosuppressive therapy (corticosteroids, cytostatics, etc.), the concurrent use of MioPets® should be only upon veterinarian’s advice.